Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hearing

Hearing

When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.

Pleiotropy

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...

Unrenewable Cells

Unrenewable Cells

In humans, the photoreceptor cells of the eye and sensory hair cells of the ear lack stem cells. These cells are thus unrenewable and cannot be replaced when they are damaged or destroyed.
Photoreceptors
The retina is composed of several layers and contains specialized cells called photoreceptors. The photoreceptors (rods and cones) change their membrane potential when stimulated by light energy. There are two types of photoreceptors—rods and cones—which differ in the shape of...

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

Changes in Skin Color: Clinical Perspectives

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

Auditory Pathway

Auditory Pathway

Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Adult Burn Survivors Face Elevated Long-Term Risk of Major Adverse Cardiovascular Events, Venous Thromboembolism, and Mortality: A Real-World Analysis.

Advances in wound care·2026

Same author

Treatments for Pediatric Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: A Critical Appraisal and Systematic Review.

The British journal of dermatology·2026

Same author

Population genomics and disease risk of primary cutaneous amyloidosis: A prominent genodermatosis of Southeast Asia.

Journal of the Formosan Medical Association = Taiwan yi zhi·2026

Same author

Adjunctive Use of VGH4 for Moderate-to-Severe Atopic Dermatitis: A Randomized, Double-Blind, Placebo-Controlled Crossover Pilot Trial.

Life (Basel, Switzerland)·2026

Same author

Comparative Effectiveness of Recombinant Zoster and Live Attenuated Zoster Vaccines in Chronic Inflammatory Skin Diseases: A Retrospective Cohort Study.

Journal of medical virology·2026

Same author

A pedunculated pink nodule on the scrotum.

Clinical and experimental dermatology·2026

Search research articles

Related Experiment Video

Updated: Nov 24, 2025

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Published on: April 11, 2025

Association between vitiligo and hearing loss.

Sheng-Hsiang Ma¹, Min-De Ang², Yun-Ting Chang¹

¹Department of Dermatology, Taipei Veterans General Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan.

Journal of the American Academy of Dermatology

|December 28, 2020

Summary

This summary is machine-generated.

Vitiligo patients have a significantly higher risk of sensorineural hearing loss (SNHL). Early audiologic assessment is recommended for individuals with vitiligo to detect and manage hearing impairments.

Keywords:

hearing loss metaanalysis sensorineural vitiligo

More Related Videos

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage

Published on: February 10, 2023

Author Spotlight: Advancements in Cultivating Mouse Hair Cells for Auditory Research

Author Spotlight: Advancements in Cultivating Mouse Hair Cells for Auditory Research

Published on: September 15, 2023

Related Experiment Videos

Last Updated: Nov 24, 2025

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Published on: April 11, 2025

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage

Published on: February 10, 2023

Author Spotlight: Advancements in Cultivating Mouse Hair Cells for Auditory Research

Author Spotlight: Advancements in Cultivating Mouse Hair Cells for Auditory Research

Published on: September 15, 2023

Area of Science:

Dermatology
Otolaryngology
Autoimmune Disorders

Background:

Vitiligo is an autoimmune condition causing melanocyte destruction.
Melanocytes in the auditory system may be involved in vitiligo.
The link between vitiligo and sensorineural hearing loss (SNHL) requires clarification.

Purpose of the Study:

To investigate the association between vitiligo and SNHL.
To conduct a systematic review and meta-analysis on vitiligo and hearing loss.

Main Methods:

Searched EMBASE, MEDLINE, PubMed, and Cochrane databases.
Included 14 case-control studies with 938 vitiligo patients.
Performed meta-analysis to determine the odds ratio (OR) for SNHL in vitiligo.

Main Results:

A significant association was found between SNHL and vitiligo (OR 6.02).
The association remained significant after adjusting for study quality and publication bias.
Adjusted ORs were 5.30 and 3.45, respectively.

Conclusions:

Current evidence supports a link between SNHL and vitiligo.
Audiologic assessment is advised for early detection and management of hearing loss in vitiligo patients.
Potential biases include heterogeneous definitions and racial differences.