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Antibiotic and bacteriologic considerations in open fractures.

M J Patzakis, D Ivler

    Southern Medical Journal
    |October 1, 1977
    PubMed
    Summary

    Open fractures are contaminated wounds. Antibiotics are crucial for treating open fractures, not just for prophylaxis, based on bacterial presence in over 60% of cases.

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    Area of Science:

    • Orthopedic Surgery
    • Infectious Diseases
    • Bacteriology

    Background:

    • Open fractures present a significant risk of infection.
    • Effective management requires understanding bacterial contamination patterns.

    Purpose of the Study:

    • To assess antibiotic and bacteriologic considerations in treating open fractures.
    • To determine the incidence of bacterial presence in open fracture wounds.

    Main Methods:

    • Prospective study of 581 open fracture cases.
    • Multiple wound cultures obtained per case.
    • Formal surgical irrigation and debridement performed.

    Main Results:

    • Bacterial organisms were identified in 62.1% of the open fracture wounds.
    • The study highlights the high prevalence of contamination.

    Conclusions:

    • Open fractures should be managed as contaminated wounds.
    • Antibiotic administration is indicated for treatment, not solely prophylaxis.

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