Related Experiment Video
Updated: Nov 24, 2025

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
Childhood maltreatment and lung function: findings from the general population
Carsten Spitzer1, Ralf Ewert2, Henry Völzke3
1Dept of Psychosomatic Medicine and Psychotherapy, University Medicine Rostock, Rostock, Germany.
Childhood maltreatment was not significantly linked to objective lung function measures like FEV1 or FVC in adults. Previous associations with asthma and COPD may stem from self-reported data rather than objective lung function.
Area of Science:
- Pulmonary Medicine
- Psychotraumatology
- Epidemiology
Background:
- Childhood maltreatment is linked to self-reported asthma and COPD.
- Objective lung function has not been assessed in relation to childhood maltreatment.
Purpose of the Study:
- To investigate the association between childhood maltreatment and objective lung function measures.
- To determine if childhood maltreatment impacts spirometry results.
Main Methods:
- 1386 adults from the general population underwent spirometry and completed the Childhood Trauma Questionnaire.
- Assessed emotional, physical, and sexual abuse, as well as emotional and physical neglect.
Main Results:
- 25.3% reported childhood maltreatment, with higher rates of obstructive airway disease medication and symptoms.
- No significant differences in forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), or FEV1/FVC ratio were found between maltreatment and non-maltreatment groups after covariate adjustment.
- No specific type of maltreatment was associated with spirometric lung function parameters.
Conclusions:
- Findings challenge the link between childhood maltreatment and obstructive lung diseases based on objective spirometry.
- Discrepancies with prior research may be due to reliance on self-reported diagnoses.
Related Concept Videos
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Other Pulmonary Disorders
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Chronic Obstructive Pulmonary Disease-I: Introduction
Statistical Methods for Analyzing Epidemiological Data
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

