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Related Concept Videos

Metastasis02:30

Metastasis

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
6.1K

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Related Experiment Video

Updated: Nov 24, 2025

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging
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Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging

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[Metastatic Brain Tumors].

Mitsuaki Shirahata1, Kazuhiko Mishima

  • 1Department of Brain and Spinal Cord Tumor, Comprehensive Cancer Center, Saitama Medical University International Medical Center.

Brain and Nerve = Shinkei Kenkyu No Shinpo
|December 28, 2020
PubMed
Summary

Metastatic brain tumors spread from other organs, impacting neurological function. Advances in radiotherapy and drug therapy are revolutionizing their treatment and improving patient outcomes.

Area of Science:

  • Oncology
  • Neurology

Background:

  • Metastatic brain tumors are secondary malignant growths in the brain originating from primary cancers elsewhere in the body.
  • These tumors significantly impair neurological function and diminish patients' quality of life.
  • Effective management of brain metastases is crucial given improving prognoses for cancer patients.

Purpose of the Study:

  • To review the clinical characteristics of metastatic brain tumors.
  • To highlight the significant advancements in the treatment of these tumors.
  • To underscore the paradigm shift in oncology due to new therapeutic strategies.

Main Methods:

  • Review of current clinical literature on metastatic brain tumors.
  • Analysis of recent progress in radiotherapy and drug therapies.

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  • Synthesis of information on the evolving clinical characterization of brain metastases.

    • Main Results:

    • Recent therapeutic advances in radiotherapy and drug therapy are transforming metastatic brain tumor treatment.
    • Improved outcomes are increasingly observed in cancer patients with brain metastases.
    • The clinical characterization and management of these tumors are at a pivotal point.

    Conclusions:

    • The treatment landscape for metastatic brain tumors has significantly evolved.
    • Advances in therapy offer new hope and improved quality of life for affected patients.
    • Continued research and clinical updates are essential in managing this complex condition.