Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Phospholipase activity in Candida albicans.

M F Price, R A Cawson

    Sabouraudia
    |July 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Candida albicans uses phospholipase A and lysophospholipase enzymes to break down phospholipids. These enzymes likely play a key role in the fungus

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Epidemiology and incidence of Clostridium difficile-associated diarrhoea diagnosed upon admission to a university hospital.

    The Journal of hospital infection·2006
    Same author

    Liposuction as an adjunct procedure in reduction mammaplasty.

    Annals of plastic surgery·2001
    Same author

    Prevalence of nasal colonization with methicillin-resistant Staphylococcus aureus in selected patient populations.

    Infection control and hospital epidemiology·2000
    Same author

    Mycobacterial disease of the parotid gland.

    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics·2000
    Same author

    Granular cell tumor in a child's finger.

    Annals of plastic surgery·2000
    Same author

    The effects of pressure-reducing mattresses in CPR.

    Nursing standard (Royal College of Nursing (Great Britain) : 1987)·1999

    Area of Science:

    • Mycology
    • Biochemistry
    • Microbial Pathogenesis

    Background:

    • Candida albicans is an opportunistic fungal pathogen.
    • Phospholipid hydrolysis is crucial for microbial invasion.
    • Enzymatic activity of Candida albicans requires investigation.

    Purpose of the Study:

    • To identify enzymes responsible for phospholipid hydrolysis in Candida albicans.
    • To describe methods for measuring phospholipase activity.
    • To discuss the role of phospholipase in epithelial invasion by Candida albicans.

    Main Methods:

    • Enzyme assays were performed to detect phospholipase A and lysophospholipase activity.
    • Specific methods were employed to quantify the measured enzymatic activities.
    • Microscopic and biochemical techniques were used to assess fungal invasion.

    Related Experiment Videos

    Main Results:

    • Phospholipase A and lysophospholipase were identified as the key enzymes.
    • The study details the methodology for identifying and measuring these enzymes.
    • Evidence suggests a significant role for phospholipase in Candida albicans epithelial invasion.

    Conclusions:

    • Phospholipase A and lysophospholipase are crucial for Candida albicans pathogenesis.
    • The described methods allow for accurate assessment of enzymatic activity.
    • Targeting these phospholipases may offer strategies to combat Candida albicans infections.