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MR-Guided Radiotherapy for Prostate Cancer.
Boris R Tocco1, Amar U Kishan2, Ting Martin Ma2
1Department of Radiotherapy, The Royal Marsden NHS Foundation Trust, London, United Kingdom.
Frontiers in Oncology
|December 28, 2020
Summary
External beam radiotherapy for prostate cancer can be improved with hypofractionation. Magnetic resonance imaging-guided radiotherapy offers enhanced accuracy for delivering these shorter, effective treatment schedules.
Area of Science:
- Oncology
- Radiotherapy
- Medical Imaging
Background:
- External beam radiotherapy is standard for localized prostate cancer.
- Hypofractionation shows promise for prostate cancer treatment due to radiobiology.
- Current image-guided techniques limit precise hypofractionated delivery.
Purpose of the Study:
- To review limitations of current image-guidance in prostate cancer radiotherapy.
- To explore the benefits and drawbacks of MR-guided radiotherapy for prostate cancer.
- To discuss MR-linac workflow and technological opportunities.
Main Methods:
- Review of current image-guidance strategies in radiotherapy.
- Analysis of magnetic resonance imaging (MRI) applications in prostate cancer treatment.
- Discussion of MR-guided linear accelerator (MR-linac) workflow and experiences.
Main Results:
- Current image-guidance has limitations for hypofractionated prostate cancer treatment.
- MR-guided radiotherapy offers improved anatomical information and daily re-planning capabilities.
- Early experiences with MR-linac show promise for accurate radiotherapy delivery.
Conclusions:
- MR-guided radiotherapy has the potential to overcome limitations in delivering hypofractionated prostate cancer treatment.
- Further investigation into MR-linac workflow is needed.
- This technology may enhance treatment accuracy and outcomes for prostate cancer patients.
