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Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells
Published on: August 25, 2021
TP53 and PTEN as driver mutations in Zenker's carcinoma-a clinical presentation
Zsanett Noel1, Sylvia Hoeller2, Michel Bihl2
1Department of Surgery University Hospitals Basel Basel Switzerland.
Abstract:
Zenker carcinoma is still being treated empirically because of the lack of evidence- based guidelines. We report for the first time about the genetic examination of this rare entity. The revealed mutations show genetic similarities with HPV(-)HNSCC which suggests that well-known therapeutic strategies may be applicable for this disease.
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