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Updated: Nov 24, 2025

Performing and Processing FNA of Anterior Fat Pad for Amyloid
Published on: October 30, 2010
Extensive amyloid deposits in bone marrow aspirate smears
Ting Hon Stanford Li1, Kit Fai Wong1, Wai Shan Wong1
1Department of Pathology Queen Elizabeth Hospital Hong Kong China.
Abstract:
Amyloid light-chain (AL) amyloidosis is the most common form of systemic amyloidosis. It can cause progressive organ dysfunction and eventually death, mainly due to cardiac involvement. Amyloidosis may rarely present as extensive amorphous, purplish-blue deposits in marrow aspirate smears. Demonstration of congophilic property and apple-green birefringence under polarized light in aspirate smears can allow a rapid diagnosis of amyloidosis.
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