A comparative study of clinical profile and symptom control in overweight and normal weight school-age children with

Sharmila Manivannan1, Venkatesh Chandrasekaran1, Nandheeswari Subramanian1

  • 1Department of Pediatrics JIPMER Puducherry India.

Health Science Reports
|December 28, 2020
PubMed

Insights

Overweight children with mild persistent asthma did not show higher rates of poor symptom control compared to normal-weight children. No significant risk factors for poor symptom control were identified in this study.

Area of Science:

  • Pediatric Pulmonology
  • Asthma Research
  • Obesity and Health

Background:

  • Mild persistent asthma affects children globally.
  • Childhood obesity is a growing concern with potential health implications.
  • Understanding asthma control in relation to weight status is crucial for effective management.

Purpose of the Study:

  • To determine the prevalence of poor symptom control in overweight/obese versus normal-weight children with mild persistent asthma.
  • To identify sociodemographic and clinical factors associated with poor symptom control in these groups.

Main Methods:

  • A case-control study involving children aged 6-12 years with mild persistent asthma.
  • Cases: overweight/obese (BMI Z-score > +1). Controls: normal weight (BMI Z-score -2 to +1).
  • Symptom control assessed using Asthma Control Test (ACT) score; lung function (FEV1, FEV1/FVC) measured.

Main Results:

  • Poor symptom control prevalence was 19.1% in overweight/obese and 23.4% in normal-weight children, with no significant difference.
  • No significant correlation found between BMI Z-score and ACT score.
  • Overweight/obese children with good control had lower FEV1/FVC and higher eosinophils; gastroesophageal reflux and allergic rhinitis were more frequent.

Conclusions:

  • Overweight/obesity status did not significantly increase the risk of poor symptom control in children with mild persistent asthma.
  • The study did not identify significant risk factors for poor symptom control in either weight group.
Abstract

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