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Asymptomatic adult Alexander's disease: entity or nosological misconception?
J E Riggs1, S S Schochet, J Nelson
1Department of Neurology, West Virginia University Medical Center, Morgantown 26506.
Neurology
|January 1, 1988
Abstract:
Two adults were found to have heavy deposits of Rosenthal fibers in the CNS after dying from severe systemic medical illnesses. Previously reported cases of neurologically asymptomatic adult Alexander's disease patients also had complicated systemic disease. We suggest that heavy Rosenthal fiber deposition may occur in the setting of severe medical illness and should not be classified as adult Alexander's disease.