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Chronic recurrent multifocal osteomyelitis.

T Brown1, R H Wilkinson

  • 1Department of Radiology, Victoria Hospital, London, Ontario, Canada.

Radiology
|February 1, 1988
PubMed
Summary
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Chronic recurrent multifocal osteomyelitis (CRMO) typically resolves in children and adolescents. However, this study found that a small number of patients may experience residual bone changes, indicating a less self-limited course for some.

Area of Science:

  • Pediatric Orthopedics
  • Rheumatology
  • Radiology

Background:

  • Chronic recurrent multifocal osteomyelitis (CRMO) is a rare inflammatory bone disorder.
  • It predominantly affects children and adolescents, often presenting with significant symptoms.
  • Historically, CRMO is considered to have a self-limited course with minimal long-term sequelae.

Purpose of the Study:

  • To evaluate the long-term outcomes of patients diagnosed with CRMO.
  • To determine the frequency of residual bone changes after CRMO.
  • To assess the clinical course and radiographic findings in a cohort of CRMO patients.

Main Methods:

  • Retrospective review of medical records and radiographic images.
  • Analysis of data from 11 patients diagnosed with CRMO.

Related Experiment Videos

  • Assessment for disease resolution and presence of residual bone abnormalities.

    • Main Results:

    • Most patients experienced symptom resolution.
    • A minority of patients (11%) exhibited persistent or residual bone changes.
    • The disease, initially reported in Europe, is increasingly recognized in North America.

    Conclusions:

    • CRMO may not always be self-limited, with potential for residual bone changes in some cases.
    • Radiographic monitoring may be necessary for a subset of CRMO patients.
    • Increased recognition of CRMO is occurring globally, including North America.