Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nipple discharge: surgical significance.

H P Leis1, F L Greene, A Cammarata

  • 1Breast Center, University of South Carolina School of Medicine, Columbia 29203.

Southern Medical Journal
|January 1, 1988
PubMed
Summary

Nipple discharge is a common breast symptom. Surgically significant discharges, like bloody or watery types, can indicate cancer or precancerous conditions, necessitating further investigation and potential surgical intervention.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thyroid hemiagenesis associated with multinodular goiter and Hashimoto's thyroiditis.

Il Giornale di chirurgia·2018
Same author

Endoluminal resection of gastric intestinal stromal tumors (GIST).

Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy·2017
Same author

Optimizing rectal cancer management: analysis of current evidence.

Diseases of the colon and rectum·2014
Same author

Staging of colon and rectal cancer: from endoscopy to molecular markers.

Surgical endoscopy·2006
Same author

Bioinformatics: a helpmate in the endoscopic age.

Surgical endoscopy·2004
Same author

The surgeon's decision as a prognostic factor in a pool of patients with colorectal cancer coming from different institutions.

Journal of experimental & clinical cancer research : CR·2003

Area of Science:

  • Breast Surgery
  • Surgical Oncology
  • Pathology

Background:

  • Nipple discharge is a frequent breast complaint, second only to breast lumps.
  • Significant nipple discharge is defined as true, spontaneous, persistent, and nonlactational.
  • Various types of nipple discharge exist, including milky, purulent, watery, serous, serosanguineous, and sanguineous.

Purpose of the Study:

  • To evaluate the clinical significance of different types of nipple discharge.
  • To determine the incidence of cancer and precancerous mastopathy associated with surgically significant nipple discharge.
  • To outline management strategies for various nipple discharge presentations.

Main Methods:

  • Retrospective analysis of 7,588 patients undergoing breast surgery.

Related Experiment Videos

  • Detailed review of 503 patients operated on for significant nipple discharge.
  • Correlation of discharge characteristics with histopathological findings, including cancer and precancerous mastopathy.

    • Main Results:

    • Among 503 surgically treated patients, 13.3% had cancer and 7.2% had precancerous mastopathy.
    • Cancer was detected in 11.9% of cases without a palpable mass and 16.4% with negative cytology.
    • The incidence of associated cancers increased with serous, serosanguineous, sanguineous, or watery discharge, and with patient age over 50.

    Conclusions:

    • Surgically significant nipple discharges warrant thorough investigation due to their association with malignancy.
    • Central duct excision is recommended for surgically significant discharges, except in specific patient groups.
    • Early diagnosis and appropriate management are crucial for favorable outcomes in patients with concerning nipple discharge.