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Endovascular Graft Infection by Neisseria meningitidis: A Rare but Fatal Infection

Ana Lopez-Marco1, Satya Das2, Robert Serafino-Wani2

  • 1Department of Cardiac Surgery, Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.

Aorta (Stamford, Conn.)
|December 28, 2020
PubMed

Insights

Endovascular graft infection is rare but serious. This case study details surgical removal and reconstruction for a thoracoabdominal aorta infection caused by the unusual bacterium Neisseria meningitidis.

Area of Science:

  • Vascular Surgery
  • Infectious Diseases
  • Microbiology

Background:

  • Endovascular graft infection is a rare complication.
  • It necessitates graft removal and arterial reconstruction.
  • Long-term antibiotic therapy is crucial.

Purpose of the Study:

  • To report a rare case of endovascular graft infection.
  • To describe the surgical management of the infected graft and aorta.
  • To highlight the unusual causative pathogen.

Main Methods:

  • Surgical explant of the infected endovascular graft.
  • Reconstruction of the thoracoabdominal aorta.
  • Microbiological analysis of the graft.

Main Results:

  • Successful surgical explant and reconstruction.
  • Identification of Neisseria meningitidis as the causative agent.
  • Neisseria meningitidis is an extremely rare cause of graft infection in this location.

Conclusions:

  • Surgical intervention is effective for endovascular graft infection.
  • Neisseria meningitidis is a highly unusual pathogen for this condition.
  • This case represents a novel finding in the literature regarding graft infections.

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