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Scurvy: A Disease not to be Forgotten
Massimo Montalto1, Enrica Porceddu1, Erika Pero1
1Department of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, Istituto di Ricovero e Cura a Carattere Scientifico - Università Cattolica del Sacro Cuore, Roma, Italy.
Scurvy, a vitamin C deficiency, can manifest with skin and bleeding issues, especially in individuals with restrictive diets or malabsorption. Consider scurvy in patients presenting with petechiae and ecchymosis, particularly those with dietary restrictions or psychiatric conditions.
Area of Science:
- Clinical Medicine
- Nutritional Science
- Dermatology
Background:
- Presents a case of an 18-year-old male with a complex medical history including anxiety-depressive disorder and self-diagnosed food allergies leading to a restrictive diet.
- The patient exhibited significant physical symptoms including muscular pain, petechiae, ecchymosis, joint swelling, subcutaneous nodules, and gingival bleeding.
- Skin lesions were characterized by hyperkeratotic papules with coiled hairs and perifollicular hemorrhages.
Observation:
- An 18-year-old male presented with muscular pain, petechiae, ecchymosis, joint swelling, subcutaneous nodules, and gingival bleeding.
- Skin examination revealed hyperkeratotic papules with coiled hairs and perifollicular hemorrhages.
- The patient reported a history of mixed anxiety-depressive disorder and a restrictive diet for self-diagnosed food allergies.
Findings:
- Low serum ascorbic acid levels confirmed a diagnosis of scurvy.
- Allergy testing revealed cross-reactivity between pollens and foods due to panallergens.
- The patient was also diagnosed with celiac disease, indicating potential malabsorption.
Implications:
- Scurvy should be included in the differential diagnosis for patients presenting with petechiae and ecchymosis.
- Identifying underlying causes like restrictive diets, malabsorption (celiac disease), or psychiatric disorders is essential for managing scurvy.
- This case highlights the importance of a comprehensive diagnostic approach for complex presentations involving nutritional deficiencies and allergies.
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