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Updated: Nov 24, 2025

Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
A Photoionization Study on the Detection of 1-Sila Glycolaldehyde (HSiOCH2 OH), 2-Sila Acetic Acid (H3 SiCOOH), and
Sankhabrata Chandra1,2, André K Eckhardt3, Andrew M Turner1,2
1Department of Chemistry, University of Hawaii at Manoa, 2545 McCarthy Mall, Honolulu, HI, 96822, USA.
Abstract:
The identification of silicon-substituted, complex organics carrying multiple functional groups by classical infrared spectroscopy is challenging because the group frequencies of functional groups often overlap. Photoionization (PI) reflectron time-of-fight mass spectrometry (ReTOF-MS) in combination with temperature-programmed desorption (TPD) holds certain advantages because molecules are identified after sublimation from the matrix into in the gas phase based on distinct ionization energies and sublimation temperatures. In this study, we reveal the detection of 1-silaglycolaldehyde (HSiOCH2 OH), 2-sila-acetic acid (H3 SiCOOH), and 1,2-disila-acetaldehyde (H3 SiSiHO)-the silicon analogues of the well-known glycolaldehyde (HCOCH2 OH), acetic acid (H3 CCOOH), and acetaldehyde (H3 CCHO), in the gas phase after preparation in silane (SiH4 )-carbon dioxide ices exposed to energetic electrons and subliming the neutral reaction products formed within the ices into the gas phase.
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