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Moyamoya disease in Taiwan.
Stroke
|January 1, 1988
Summary
Moyamoya disease in Chinese adults, predominantly males, presents with hemorrhagic strokes and intraventricular hemorrhage. This contrasts with Japanese series, highlighting unique demographic and clinical features.
Area of Science:
- Neurology
- Neuroimaging
- Vascular Neurology
Background:
- Moyamoya disease (MMD) in the Chinese population is not well-documented.
- Previous Chinese studies suggest subarachnoid hemorrhage as the primary clinical manifestation.
Purpose of the Study:
- To describe the clinical and angiographic features of Moyamoya disease in a Chinese cohort.
- To compare these findings with previously reported series, particularly from Japan.
Main Methods:
- Retrospective review of 3,200 cerebral angiograms conducted between August 1979 and March 1986.
- Analysis of 13 identified cases of Moyamoya disease, including demographic, clinical, and imaging data.
Main Results:
- The study identified 13 cases (9 males, 4 females), predominantly adults (12) aged 34-51 years.
- Hemorrhagic strokes were the main presentation (12/13), with frequent intraventricular hemorrhage (10/13) and intracerebral hematoma (7/13).
- Angiography revealed characteristic smokelike basal anastomoses, bilateral involvement in 12 cases, and stenosis/occlusion of the circle of Willis.
Conclusions:
- This Chinese cohort exhibits a male predominance and a high incidence of hemorrhagic stroke with intraventricular hemorrhage, differing from Japanese series.
- The findings suggest distinct epidemiological and clinical characteristics of Moyamoya disease in the Chinese population.