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Updated: Nov 24, 2025
Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
Published on: May 30, 2025
Sildenafil Misuse for its Psychoactive Properties? A Case Report
Rahul Mathur1, Arpit Parmar, Surendra Singh Rajpurohit
1National Drug Dependence Treatment Centre and Department of Psychiatry, All India Institute of Medical Sciences, New Delhi - 29, India (RM, SS, TT, RB, RR); Department of Psychiatry and Drug De-addiction and Treatment Center, All India Institute of Medical Sciences, Bhubaneswar, India (AP).
Abstract:
Sildenafil is a widely used drug for the treatment of erectile dysfunction in a dosage ranging from 50 to 100 mg per day. Recreational use is reported among youth for its sexual function enhancing effects. To date, however, no study has reported the use of sildenafil for its nonsexual, psychoactive effects. We report a case of a 38-year-old male with opioid and sedative use disorder who self-administered sildenafil orally in a dose of up to 2000 mg per day for its psychoactive effects (primarily) for 10 years before seeking treatment and discuss the literature relevant to the case.
