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Related Experiment Videos

The Activitrax rate responsive pacemaker system.

K den Dulk1, L Bouwels, F Lindemans

  • 1Department of Cardiology, Academic Hospital Meastricht, University of Limburg, The Netherlands.

The American Journal of Cardiology
|January 1, 1988
PubMed
Summary
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Medtronic Activitrax pacemakers effectively mimicked natural heart rates during daily activities and exercise in patients with heart rhythm disorders. These rate-responsive pacemakers demonstrated close correlation with sinus rhythm, ensuring appropriate pacing without inducing arrhythmias.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Electrophysiology

Background:

  • Bipolar Medtronic Activitrax pacemakers were implanted in 31 patients for ventricular or atrial pacing.
  • Indications included His bundle ablation (20), sick sinus syndrome (7), atrioventricular block (1), and combined sick sinus syndrome with atrioventricular block (3).

Purpose of the Study:

  • To evaluate the performance of Medtronic Activitrax rate-responsive pacemakers.
  • To assess the correlation between pacemaker-driven heart rate and underlying sinus rate during various activities.

Main Methods:

  • Implantation of 31 Medtronic Activitrax pacemakers.
  • Follow-up averaging 16 months.
  • 24-hour ambulatory electrocardiographic monitoring with diary.
  • Treadmill exercise tests (20 patients) and a 20-minute circuit walk (11 patients).

Related Experiment Videos

  • Comparison of pacemaker rate with sinus rate during exercise and car driving.

    • Main Results:

    • Pacing rate closely matched underlying sinus rate during exercise in 9 patients.
    • Pacing rate during car driving was similar to sinus rates in volunteers (mean 80-99 pulses/min).
    • No pacing-induced arrhythmias were observed.
    • Minor issues like irregular pacing intervals due to polarization sensing and a resolved timing anomaly were noted but had no clinical consequence.

    Conclusions:

    • Medtronic Activitrax pacemakers provide appropriate rate-responsive pacing.
    • The device effectively mimics physiological heart rate responses during daily activities and exercise.
    • Reprogramming can resolve minor technical issues, ensuring clinical efficacy.