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Updated: Nov 24, 2025

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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Early Left Ventricular Diastolic Dysfunction and Abnormal Left Ventricular-left Atrial Coupling in Asymptomatic

Yanyan Song1, Lu Li1, Xiuyu Chen1

  • 1Department of Magnetic Resonance Imaging, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing.

Journal of Thoracic Imaging
|December 28, 2020
PubMed

Insights

Cardiovascular magnetic resonance feature-tracking (CMR-FT) detects early left ventricular (LV) diastolic dysfunction in hypertension patients. This dysfunction is linked to impaired left atrial (LA) function, aiding early diagnosis.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Hypertension (HTN) is associated with increased risk of left ventricular (LV) diastolic dysfunction and hypertrophy (LVH).
  • Accurate noninvasive tools are crucial for evaluating early LV diastolic function in HTN patients.

Purpose of the Study:

  • To assess cardiovascular magnetic resonance feature-tracking (CMR-FT) for detecting early LV diastolic dysfunction in HTN.
  • To evaluate the correlation between LV and left atrial (LA) dysfunction in HTN patients using CMR-FT.

Main Methods:

  • Retrospective analysis of 89 HTN patients and 38 controls using CMR.
  • Categorization of HTN patients into LVH (n=38) and non-LVH (n=51) groups.
  • Analysis of LV and LA deformation parameters, including peak diastolic strain rate (PDSR) and LA reservoir/conduit/booster pump functions.

Main Results:

  • HTN patients showed impaired LV PDSR and LA reservoir/conduit function compared to controls, irrespective of LVH (P<0.05).
  • LV longitudinal and radial PDSR correlated significantly with LA reservoir and conduit function (P<0.01).
  • Longitudinal PDSR and LA conduit function (εe) were sensitive indicators for differentiating non-LVH patients from controls, with combined analysis yielding an AUC of 0.81.

Conclusions:

  • CMR-FT effectively detects early LV diastolic dysfunction in HTN patients.
  • The observed LV diastolic dysfunction in HTN is associated with impaired LA reservoir and conduit function.
Abstract

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