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Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
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Update on food allergy.

Rachel L Peters1,2, Marta Krawiec3,4,5, Jennifer J Koplin1,2,6

  • 1Murdoch Children's Research Institute Melbourne, Melbourne, Vic., Australia.

Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
|December 28, 2020
PubMed
Summary

Food allergy prevalence is rising globally. Early introduction of allergenic foods during weaning and new treatments like immunotherapy offer hope for prevention and management.

Keywords:
IgEbasophil activation testbiologicsdiagnosisfood allergyimmunotherapyskin prick test

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Area of Science:

  • Immunology
  • Public Health
  • Pediatrics

Background:

  • Food allergy represents a significant and increasing global public health concern.
  • The rising prevalence impacts patients and families, necessitating research into causative factors and immune mechanisms.
  • Understanding risk factors is crucial for developing effective prevention and treatment strategies.

Purpose of the Study:

  • To explore the growing prevalence and impact of food allergies.
  • To identify key risk factors and underlying immune mechanisms contributing to food allergy development.
  • To review current and emerging strategies for food allergy prevention and management.

Main Methods:

  • Literature review of epidemiological data on food allergy prevalence.
  • Analysis of research on immune responses related to food allergens.
  • Examination of clinical trial data for new therapeutic interventions.

Main Results:

  • Early introduction of allergenic foods, such as peanuts, during weaning is a demonstrated preventive measure.
  • Advancements in diagnosis, food immunotherapy, and biologics are transitioning into clinical practice.
  • Personalized management plans incorporating patient and family preferences are essential.

Conclusions:

  • Current evidence supports early allergen introduction for food allergy prevention.
  • Emerging treatments like immunotherapy and biologics offer new avenues for managing existing food allergies.
  • Tailored patient care, considering individual preferences, is vital for effective food allergy management.