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Updated: Nov 24, 2025

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
Published on: August 21, 2017
Infliximab-induced optic neuritis
Andrew Dermawan1, Kenji So2, Kannan Venugopal2
1Department of Gastroenterology, Royal Perth Hospital, Perth, Western Australia, Australia andrew.dermawan@health.wa.gov.au.
Abstract:
Antitumour necrosis factor alpha agents are important treatments in many inflammatory conditions including rheumatoid arthritis, psoriatic arthritis and the inflammatory bowel diseases. However, there have been case reports of optic neuritis and other demyelinating diseases as complications of these agents. This case report presents a patient with ulcerative colitis on infliximab who presented with sudden onset mono-ocular visual field loss and highlights the diagnosis and management of infliximab-induced optic neuritis.
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