HLA and the probability of paternity

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R Borowsky1

  • 1Department of Biology, New York University, Washington Square 10003.

American Journal of Human Genetics
|January 1, 1988
PubMed

In cases of disputed paternity, blood tests are often used to obtain an estimate of the probability that the accused male is the true father. The interpretation of the genetic data is usually based upon a statistic called the paternity index. This paper shows that the paternity index method cannot be applied to data from compound loci in the absence of information on linkage phase. Since phenotypic data from compound loci, such as HLA, MNSs, and Rh, are often useful in disputed paternity proceedings, they should be analyzed with available alternative statistics.

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