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Multidisciplinary diagnosis and treatment of recurrent follicular dendritic cell sarcoma in abdomen: A case report
Chang Qu1, Xiaodong Tian1, Yongsu Ma1
1Department of General Surgery.
Rationale:
Follicular dendritic cell sarcoma (FDCS) is a rare malignant tumor derived from follicular dendritic cells, and is often associated with Castleman disease. Here we present a rare case of paraneoplastic pemphigus (PNP) with FDCS which required multidisciplinary approach for the diagnosis and treatment.
Patient Concerns:
A 28-year-old Chinese female had FDCS recurrence, and primary clinical manifestation was PNP.
Diagnoses:
PNP with FDCS.
Interventions:
The patient received gamma globulin infusion, took anlotinib, and underwent plasma exchange therapy.
Outcomes:
The skin lesions recovered and there was no evidence of tumor recurrence.
Lessons:
The diagnosis and management of PNP with FDCS require close cooperation among surgeons, dermatologists, hematologists, otolaryngologists, oncologists, radiologists, pathologists, and respiratory doctors. The interesting clinical manifestations of this patient provide a multifaceted approach to the investigation of the interactions among FDCS, Castleman disease, and PNP.