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Exploring the neural correlates of self-related names in healthy subjects
Ran Li1, Jubao Du, Weiguan Chen
1Department of Rehabilitation Medicine, Xuan Wu Hospital, Capital Medical University, Beijing, P. R.China.
Objectives:
This study aimed to clarify the neural correlates and underlying mechanisms of the subject's own name (SON) and the unique name derived from the SON (SDN).
Methods:
A name that was most familiar to the subject (SFN) was added as a self-related reference. We used 4 auditory stimuli-pure tone (1000 Hz), SON, SDN, and SFN-to evaluate the corresponding activated brain areas in 19 healthy subjects by using functional magnetic resonance imaging.
Results:
Our results demonstrated that pure tone activated the fewest brain regions. Although SFN was a very strong self-related stimulus, it failed to activate many midline structures. The brain regions activated by SON and SDN were very similar. SFN as a self-related stimulus was less self-related compared with SDN. What's more, the additionally activated fusiform gyrus and parahippocampal gyrus of SDN might revealed its processing path.
Conclusions:
SDN, which has created by us, is a new and self-related stimulus similar to SON. They might provide a useful reference for consciousness assessment with SON and SDN.
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