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Study protocol epidemiology of inflammatory bowel disease in childhood and adolescence: a systematic review
Jens Weidner1, Ivana Kern2, Ulf Manuwald2
1Faculty of Medicine "Carl Gustav Carus", Health Sciences/ Public Health, Technische Universität Dresden, Dresden, Germany jens.weidner@tu-dresden.de.
Insights
Chronic inflammatory bowel diseases (IBD) are rising in children and adolescents globally. This review analyzes international epidemiological trends from 1970-2019, highlighting geographical variations in IBD incidence.
Area of Science:
- Pediatric Gastroenterology
- Epidemiology
- Public Health
Background:
- Chronic inflammatory bowel diseases (IBD) present a growing global health concern.
- Incidence and prevalence rates of pediatric IBD show significant international variation.
Purpose of the Study:
- To systematically review and describe international epidemiological trends of IBD in children and adolescents.
- To present geographical differences in the development of IBD incidence from 1970 to 2019.
Main Methods:
- Systematic literature search of PubMed and Embase databases (1970-2019).
- Manual search of bibliographies of relevant systematic reviews.
- Qualitative and quantitative synthesis and statistical evaluation of included studies.
Main Results:
- Data synthesis will reveal current epidemiological trends in pediatric IBD.
- Geographical variations in IBD incidence will be quantified and presented.
- Analysis will cover a significant historical period (1970-2019).
Conclusions:
- Understanding global IBD trends is crucial for public health strategies.
- This review will provide valuable insights into the epidemiology of pediatric IBD worldwide.
- Findings will inform clinical practice and future research directions.
Introduction:
The incidence and prevalence of chronic inflammatory bowel diseases in childhood and adolescence is increasing and varies internationally. The systematic literature review aims to describe international epidemiological trends of chronic inflammatory bowel diseases in the child and adolescence age. A period from 1970 to 2019 will be taken into account when searching for suitable studies as well as geographical differences in the development of incidences will be presented.
Methods And Analysis:
The literature databases PubMed and Embase will be searched for the period from 01 January 1970 to 31 December 2019 using linked keywords. A manual search in bibliographies of already published and relevant systematic reviews will complete the systematic literature search. The included studies will be combined in a qualitative and quantitative synthesis and statistically evaluated.
Ethics And Dissemination:
Ethical approval is not required for this study as it is a systematicreview. The results will be submitted to peer-reviewed journals and presented in national andinternational meetings. This research received no specific grant from any funding agency inthe public, commercial or not-for-profit sectors. This systematic review protocol was registeredwith the International Prospective Register of Systematic Reviews (PROSPERO-NR:CRD42020168644).
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