Related Experiment Video
Updated: Nov 24, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Risk factors of the severity of COVID-19: A meta-analysis
Abdur Rahman1, Nusrat Jahan Sathi1
1Statistics Discipline, Science, Engineering and Technology School, Khulna University, Khulna, Bangladesh, 9208, Bangladesh.
Objective:
We intend to identify some probable risk factors that are responsible for the severity of COVID-19 using a meta-analysis.
Methods:
The literature exploration lasted up to 18 April 2020 and through PubMed, Google Scholar, EMBASE and Cochrane Library we have identified 10 pertinent publications. To paraphrase the outcomes of autonomous researches, we have performed a random-effect meta-analysis.
Results:
A total of 2272 patients' information was extracted from the selected literature. We have found gender (male) (Risk ratio [RR] = 1.29, 95% Confidence Interval [CI] 1.07 to 1.54), hypertension (RR = 1.79, 95% CI 1.57 to 2.04), diabetes (RR = 1.57, 95% CI 1.25 to 1.98), fatigue or myalgia (RR = 1.17, 95% CI 1.02 to 1.35), and smoking history (RR = 1.71, 95% CI 1.25 to 2.35) are potential risk factors for the severity of COVID-19. We found fever (RR = 1.21, 95% CI 0.66 to 2.22), cough (1.13, 95% CI 0.98 to 1.30) and diarrhoea (RR = 1.14, 95% CI 0.93 to 1.40) as insignificant risk factors for COVID-19 severity.
Conclusions:
The findings of this research may be beneficial to identify patients with higher risks to provide additional medical attention from the very beginning of the treatment.
More Related Videos
Related Concept Videos
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Coronary Artery Disease I: Introduction
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Bias in Epidemiological Studies
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...

