Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Persuasion Strategies01:52

Persuasion Strategies

Researchers have tested many persuasion strategies, including the foot-in-the door and the door-in-the-face techniques, in a variety of contexts. Ultimately, the principles are effective in selling products and changing people’s attitude, ideas, and behaviors (Cialdini & Goldstein, 2004).
The Nucleolus02:55

The Nucleolus

The nucleolus is the most prominent substructure of the nucleus. When it was first discovered, it was considered to be an isolated organelle that forms fibrils and granules. In 1931, the relationship between the nucleolus and chromosomes was first described by Heitz. He observed that the appearance and size of nucleolus varies depending on the stage of the cell cycle. He also noticed constricted regions on different chromosomes clustered together at definite cell cycle stages. These regions,...
In-situ Hybridization02:31

In-situ Hybridization

In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
Types of probes and labels
A probe is a complementary strand of DNA or RNA that binds to corresponding nucleotide sequences in a cell. Many...
The Nucleolus02:55

The Nucleolus

The nucleolus is the most prominent substructure of the nucleus. When it was first discovered, it was considered to be an isolated organelle that forms fibrils and granules. In 1931, the relationship between the nucleolus and chromosomes was first described by Heitz. He observed that the appearance and size of nucleolus varies depending on the stage of the cell cycle. He also noticed constricted regions on different chromosomes clustered together at definite cell cycle stages. These regions,...
Stratified Sampling Method01:16

Stratified Sampling Method

Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. The sampling method ensures that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest.
To choose a stratified sample, divide the population into groups called strata and then take a...
Stokes' Law01:20

Stokes' Law

Viscous forces, like friction, are intermolecular forces that resist the relative motion of molecules over each other. When a solid body moves through a liquid, viscous forces drag it in the opposite direction. The force's magnitude depends on the solid's shape and size, as well as its speed and the liquid's coefficient of viscosity, density and temperature.
The expression for the force on a solid spherical object in a fluid is called Stokes' law. Stokes' law is valid only for low Reynolds...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanism of Photoinduced Conformational Changes in the Photoenzyme Fatty Acid Photodecarboxylase Revealed by Light- Footprinting Ion Mobility Mass Spectrometry.

Journal of the American Chemical Society·2026
Same author

Integrated structural dynamics uncover a new B<sub>12</sub> photoreceptor activation mode.

Nature·2026
Same author

Enhanced bioproduction and processing of mandelic acid enantiomers: towards a sustainable platform for high-value pharmaceutical and polymer applications.

Biotechnology for biofuels and bioproducts·2025
Same author

Expanding the substrate scope of a bacterial monoterpene synthase for the production of sesquiterpenoid and diterpenoid products.

The FEBS journal·2025
Same author

<i>De Novo</i> Production of Xanthohumol by a Metabolically Engineered <i>Escherichia coli</i>.

ACS synthetic biology·2025
Same author

Structural and functional insights into a novel aldehyde deformylating oxygenase with enhanced efficiency for biofuel applications.

The FEBS journal·2025

Related Experiment Video

Updated: Jun 20, 2026

The Neuromuscular Junction: Measuring Synapse Size, Fragmentation and Changes in Synaptic Protein Density Using Confocal Fluorescence Microscopy
12:18

The Neuromuscular Junction: Measuring Synapse Size, Fragmentation and Changes in Synaptic Protein Density Using Confocal Fluorescence Microscopy

Published on: December 26, 2014

22.2K

In conversation with Nigel Scrutton.

Paraminder Dhillon1, Nigel S Scrutton2

  • 1The FEBS Journal Editorial Office, St Andrew's House, Cambridge, UK.

The FEBS Journal
|December 29, 2020
PubMed
Summary

Professor Nigel Scrutton

Area of Science:

  • Molecular Enzymology and Biophysical Chemistry
  • Biotechnology and Biomanufacturing
  • Synthetic Biology

Background:

  • Professor Scrutton's foundational research in enzyme redesign at Cambridge.
  • His academic career progression, including positions at Leicester and Manchester.
  • Establishment of key research centers: SYNBIOCHEM and the UK Future Biomanufacturing Research Hub.

Discussion:

  • The interview highlights the critical role of fundamental enzymatic catalysis studies.
  • Explores how these studies drive advancements in biotechnology and biomanufacturing.
  • Discusses the influence of formative experiences and mentors on his career trajectory.

Key Insights:

  • Enzyme engineering and biocatalysis are central to modern biomanufacturing.

More Related Videos

Combining Double Fluorescence In Situ Hybridization with Immunolabelling for Detection of the Expression of Three Genes in Mouse Brain Sections
09:23

Combining Double Fluorescence In Situ Hybridization with Immunolabelling for Detection of the Expression of Three Genes in Mouse Brain Sections

Published on: March 26, 2016

14.3K
Author Spotlight: High-Sensitivity Tissue Factor Activity Assay for Plasma Diagnosis
03:53

Author Spotlight: High-Sensitivity Tissue Factor Activity Assay for Plasma Diagnosis

Published on: December 29, 2023

1.1K

Related Experiment Videos

Last Updated: Jun 20, 2026

The Neuromuscular Junction: Measuring Synapse Size, Fragmentation and Changes in Synaptic Protein Density Using Confocal Fluorescence Microscopy
12:18

The Neuromuscular Junction: Measuring Synapse Size, Fragmentation and Changes in Synaptic Protein Density Using Confocal Fluorescence Microscopy

Published on: December 26, 2014

22.2K
Combining Double Fluorescence In Situ Hybridization with Immunolabelling for Detection of the Expression of Three Genes in Mouse Brain Sections
09:23

Combining Double Fluorescence In Situ Hybridization with Immunolabelling for Detection of the Expression of Three Genes in Mouse Brain Sections

Published on: March 26, 2016

14.3K
Author Spotlight: High-Sensitivity Tissue Factor Activity Assay for Plasma Diagnosis
03:53

Author Spotlight: High-Sensitivity Tissue Factor Activity Assay for Plasma Diagnosis

Published on: December 29, 2023

1.1K
  • Fundamental biophysical chemistry research underpins biotechnological innovation.
  • The synergy between discovery-led science and application-focused research is crucial.

    • Outlook:

    • Continued leadership in enzyme engineering and synthetic biology.
    • Further integration of biophysics into biomanufacturing solutions.
    • Translating fundamental enzymatic mechanisms into industrial applications.