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Related Experiment Video

Updated: Nov 23, 2025

Measurement of Basal and Forskolin-stimulated Lipolysis in Inguinal Adipose Fat Pads

Measurement of Basal and Forskolin-stimulated Lipolysis in Inguinal Adipose Fat Pads

Published on: July 21, 2017

Cryolipolysis-induced abdominal fat change: Split-body trials.

In Cheol Hwang¹, Kyoung Kon Kim¹, Kyu Rae Lee¹

¹Family Medicine, Gachon University, Incheon, Korea.

|December 29, 2020

Summary

A single cryolipolysis session effectively reduced visceral adipose tissue in the abdomen by 15.6% after 12 weeks. This noninvasive treatment also showed trends in reducing overall body fat and waist circumference.

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Area of Science:

Dermatology
Aesthetics
Body Contouring

Background:

Cryolipolysis is a noninvasive method for reducing subcutaneous fat.
Previous studies lacked 12-week data on cryolipolysis effects on abdominal fat tissue.

Purpose of the Study:

To investigate the effects of a single unilateral cryolipolysis session on visceral and subcutaneous adipose tissue over 12 weeks.
To compare treated and untreated abdominal areas using computed tomography.

Main Methods:

A split-body trial involving 15 participants (9 women).
Computed tomography scans measured abdominal adipose tissue cross-sectional areas before and 12 weeks after treatment.
Waist circumference and body fat percentage were measured at baseline, 6, and 12 weeks.

Main Results:

Visceral adipose tissue (VAT) on the treated side significantly decreased by 15.6% (6.8 cm2; P = 0.003).
Overall VAT area tended to decrease by 9.9% (8.4 cm2).
Waist circumference and body fat percentage also showed overall reductions.

Conclusions:

A single session of cryolipolysis is a safe and effective treatment for reducing visceral adipose tissue.
The reduction in visceral fat suggests potential for metabolic improvements.