Black Phosphorus as Multifaceted Advanced Material Nanoplatforms for Potential Biomedical Applications

Area of Science:

• Materials Science
• Nanotechnology
• Biomedical Engineering

Background:

• Black phosphorus (BP) is an emerging two-dimensional (2D) material with anisotropic properties and an infrared bandgap.
• BP has demonstrated potential in diverse fields, including optoelectronics, 3D printing, and bioimaging.
• Its unique characteristics make it a promising candidate for advanced biomedical applications.

Purpose of the Study:

• To provide a comprehensive overview of black phosphorus (BP) synthesis and properties.
• To discuss surface modifications for enhancing BP stability and targeting capabilities.
• To review characterization techniques for assessing BP and its nanocomposites.
• To explore the biomedical applications of BP-based nanoplatforms, particularly in drug delivery, 3D printing, wound dressing, and cancer therapy.

Main Methods:

• Review of synthetic approaches for black phosphorus (BP).
• Discussion of surface modification strategies for BP nanoplatforms.
• Overview of spectroscopic, thermal, optical, and electron microscopic characterization techniques.
• Detailed examination of BP's role in drug delivery, 3D printing, wound dressing, and cancer therapy.

Main Results:

• Black phosphorus (BP) exhibits versatile properties suitable for biomedical applications.
• Surface modifications can improve BP stability and enable targeted drug delivery.
• Characterization techniques are crucial for understanding BP's fundamental properties and structural integrity.
• BP-based nanoplatforms show significant potential in cancer therapy and bioimaging.

Conclusions:

• Black phosphorus (BP) and its derivatives offer multifunctional capabilities for various biomedical applications.
• BP-based nanoplatforms are promising for theranostics, particularly in cancer treatment and imaging.
• Further research is ongoing to develop advanced BP-based theranostic platforms for diverse diseases.