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Related Experiment Videos

Retinoschisis associated with optic nerve pits.

H Lincoff1, R Lopez, I Kreissig

  • 1Department of Ophthalmology, New York Hospital, Cornell Medical Center, NY 10021.

Archives of Ophthalmology (Chicago, Ill. : 1960)
|January 1, 1988
PubMed
Summary

Retinal elevation linked to optic pits often involves schisis-like separation of inner retinal layers. This finding was observed in most studied eyes with optic pits and maculopathy.

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Area of Science:

  • Ophthalmology
  • Retinal imaging
  • Pathology

Background:

  • Optic pits are congenital abnormalities.
  • Maculopathy can be associated with optic pits.
  • Understanding the structural changes is crucial for diagnosis.

Observation:

  • Stereoscopic transparencies were analyzed using magnification and projection.
  • Retinal elevation communicating with optic pits was examined.
  • The internal and external retinal layers were assessed.

Findings:

  • Retinal elevation associated with optic pits frequently presents as a schisis-like separation of the internal retinal layers.
  • This schisis pattern was identified in 13 out of 15 eyes with optic pits and maculopathy.
  • Separation of the outer retinal layers appears to be a secondary event originating in the macula.

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Implications:

  • This detailed understanding of retinal anatomy in optic pit maculopathy can aid in diagnosis.
  • The findings may influence the management strategies for patients with optic pits.
  • Further research into the pathogenesis of schisis in optic pit maculopathy is warranted.