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Updated: Nov 23, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Interventional Treatment for Stroke Prevention
Carola Gianni1, Domenico G Della Rocca1, Andrea Natale1,2,3,4
1Texas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin, TX, USA.
Insights
Left atrial appendage closure with devices prevents strokes in high-risk patients. This review covers practical aspects of five transcatheter occlusion devices: Watchman, Amulet, WaveCrest, LAmbre, and Lariat.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Left atrial appendage (LAA) occlusion is an alternative to oral anticoagulation for stroke prevention.
- Patients with high stroke risk or contraindications to anticoagulation are candidates for LAA closure.
Purpose of the Study:
- To discuss the practical aspects of interventional LAA occlusion.
- To review five commonly used LAA occlusion devices.
Main Methods:
- Review of available percutaneous transcatheter occlusion devices.
- Discussion of practical considerations for device implantation.
Main Results:
- Five LAA occlusion devices are available: Watchman, Amulet, WaveCrest, LAmbre, and Lariat.
- Each device has unique practical aspects relevant to implantation and patient selection.
Conclusions:
- Percutaneous LAA occlusion offers a viable stroke prevention strategy.
- Understanding the practical nuances of different devices is crucial for successful implementation.
Abstract:
Closure of the left atrial appendage using percutaneous transcatheter occlusion devices is used for stroke prevention as an alternative for patients with a high risk or contraindications for long-term oral anticoagulation use. Herein, we will discuss the practical aspects of five among the available devices used for interventional left atrial appendage occlusion: Watchman, Amulet, WaveCrest, LAmbre, and Lariat.
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