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[Correlation between gut microbiota and erectile dysfunction: An update].

Yuan Sun1, Shi-Qi Pei1, Xiao-Wei Guo1

  • 1Department of Andrology, The First Affiliated Hospital of Tianjin University of Chinese Medicine, Tianjin 300193, China.

Zhonghua Nan Ke Xue = National Journal of Andrology
|December 30, 2020
PubMed
Summary
This summary is machine-generated.

The gut microbiome influences erectile dysfunction (ED) risk factors like stress and obesity. This review explores gut microbiota

Keywords:
androgenerectile dysfunctionmental psychologyneurotransmitterthyroid functionvascular endotheliumgut microbiota

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Area of Science:

  • Microbiology
  • Medical Research
  • Human Health

Background:

  • Gut microbiota is increasingly recognized for its role in health and disease.
  • Existing research links gut microbiota to erectile dysfunction (ED) risk factors, including stress, anxiety, hormonal imbalances, obesity, diabetes mellitus, and thyroid dysfunction.

Purpose of the Study:

  • To review the correlation between gut microbiota and ED.
  • To investigate the influence of gut microbiota on mental psychology, neurotransmitters, vascular endothelium, androgen function, and thyroid function in relation to ED.
  • To propose novel research directions for ED pathogenesis and treatment.

Main Methods:

  • Literature review of studies examining the gut microbiota and ED.
  • Analysis of the interplay between gut microbial composition and various physiological and psychological factors associated with ED.

Main Results:

  • The gut microbiome is implicated in ED through its effects on stress, anxiety, and hormonal regulation.
  • Alterations in gut microbiota can impact neurotransmitter levels and vascular endothelial function, both critical for erectile function.
  • Dysbiosis may contribute to ED via disruptions in androgen and thyroid hormone homeostasis.

Conclusions:

  • Gut microbiota plays a significant role in the development of ED.
  • Understanding the gut microbiota's influence offers new avenues for diagnosing and treating ED.
  • Targeting the gut microbiome may represent a promising therapeutic strategy for ED.