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Related Experiment Videos

Significant changes in Ritchie scores.

P A Lewis1, M M O'Sullivan, W R Rumfeld

  • 1Department of Rheumatology, University Hospital of Wales, Heath Park, Cardiff, UK.

British Journal of Rheumatology
|February 1, 1988
PubMed
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This study on rheumatoid arthritis joint tenderness found high reliability between and within observers. Clinically significant changes in joint tenderness scores require careful interpretation of confidence intervals for accurate patient assessment.

Area of Science:

  • Rheumatology
  • Clinical Metrology

Background:

  • Assessing joint tenderness is crucial in rheumatoid arthritis (RA) management.
  • Establishing reliable measurement tools is essential for clinical trials and patient care.

Purpose of the Study:

  • To determine the reliability of joint tenderness assessments in rheumatoid arthritis.
  • To calculate the 95% confidence intervals (CI) for score changes within and between observers.

Main Methods:

  • Forty-two RA patients were assessed over 14 weeks.
  • Two metrologists performed assessments three times weekly.
  • Intra- and inter-observer reliability and 95% CIs for score changes were calculated.

Main Results:

  • Close agreement was observed within and between metrologists.

Related Experiment Videos

  • The 95% CI for repeat measures was +/- 8.5 (same metrologist) and +/- 12 (different metrologist).
  • A clinically significant change (score change of 5) had a 95% CI of +/- 14 (one observer) and +/- 17 (different observers).

    • Conclusions:

    • The assessment of joint tenderness in RA demonstrates good reliability.
    • Confidence intervals for score changes are vital for interpreting clinical significance.
    • Other centers should establish their own CIs for score changes in clinical trials.