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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Electron Microscope Tomography and Single-particle Reconstruction01:07

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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
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Imaging Biological Samples with Optical Microscopy01:18

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Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
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Imaging Studies III: Computed Tomography01:27

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Positron Emission Tomography01:29

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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
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Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview01:13

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Attenuated total reflectance (ATR) infrared spectroscopy is a powerful analytical technique used to study the composition of materials. It is widely employed in chemistry, materials science, forensic science, and other fields where sample characterization is required. ATR has several advantages over traditional transmission IR spectroscopy, including the requirement of little to no sample preparation and the ability to analyze a wide range of samples.
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Related Experiment Video

Updated: Nov 23, 2025

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
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Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

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Spectrally sparse optical coherence tomography.

Okan Atalar, David S Millar, Pu Wang

    Optics Express
    |December 31, 2020
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces spectrally sparse optical coherence tomography (OCT) using low-cost devices. This innovation enables accurate distance estimation and imaging, making OCT more accessible for new applications.

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    Area of Science:

    • Biomedical Optics
    • Optical Engineering
    • Signal Processing

    Background:

    • Swept-source optical coherence tomography (OCT) traditionally requires expensive lasers, limiting its widespread adoption.
    • High costs associated with specialized swept-source lasers hinder the exploration of OCT in novel applications.

    Purpose of the Study:

    • To demonstrate a cost-effective spectrally sparse OCT system.
    • To achieve high-resolution distance estimation and imaging using affordable components.

    Main Methods:

    • Utilized randomly spaced, low-bandwidth optical chirps for spectrally sparse OCT.
    • Implemented a stepped chirp approach with 23% bandwidth occupancy for distance estimation.
    • Evaluated performance on metallic targets in sparse scenes.

    Main Results:

    • Achieved micron-scale distance estimation accuracy.
    • Demonstrated a resolution of 40 μm at imaging distances over 10 cm.
    • Verified comparable performance to full-bandwidth OCT for sparse metallic targets.

    Conclusions:

    • Spectrally sparse OCT with low-bandwidth chirps offers a viable low-cost alternative to traditional OCT.
    • This approach expands the potential applications of OCT by reducing hardware costs.
    • The demonstrated system provides high accuracy and resolution suitable for various imaging tasks.