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Osteomyelitis due to Kingella kingae infection
Canadian Journal of Surgery. Journal Canadien De Chirurgie
|January 1, 1988
Abstract:
A case of osteomyelitis due to Kingella kingae is presented to illustrate the insidious onset and indolent course typical of bone infections caused by this organism. The frequently negative result obtained with Gram's stain and the fastidious nature of the organism makes diagnosis difficult. Initial therapy with an aminopenicillin such as ampicillin in addition to antimicrobial drugs for Staphylococcus aureus should be effective in resolving bone and joint infections in children.
Insights
Kingella kingae can cause difficult-to-diagnose bone infections in children. Early treatment with ampicillin and Staphylococcus aureus drugs is recommended for effective resolution.
Area of Science:
- Pediatric infectious diseases
- Bacterial osteomyelitis
- Microbiology
Background:
- Osteomyelitis is a serious bone infection, particularly in children.
- Kingella kingae is an emerging pathogen causing bone and joint infections.
- Diagnostic challenges exist for fastidious bacterial organisms.
Observation:
- A case of osteomyelitis caused by Kingella kingae is presented.
- The infection exhibited an insidious onset and slow progression.
- Gram staining often yields negative results for this organism.
Findings:
- Kingella kingae presents diagnostic difficulties due to its fastidious nature and common negative Gram stain results.
- Effective initial therapy involves aminopenicillins (e.g., ampicillin) alongside treatments for Staphylococcus aureus.
- This therapeutic approach aids in resolving pediatric bone and joint infections.
Implications:
- Highlights the importance of considering Kingella kingae in pediatric bone infections.
- Emphasizes the need for advanced diagnostic methods when initial tests are negative.
- Guides appropriate antimicrobial selection for successful treatment outcomes.