The Effect of Bariatric Surgery and Endoscopic Procedures on Gastroesophageal Reflux Disease
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Updated: Nov 23, 2025

Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Ofer Z Fass1, Hiroshi Mashimo2
1Department of Medicine, New York University Langone Health, New York, NY, USA.
Abstract:
Obesity is a global epidemic posing a significant burden on patients and healthcare systems. Gastroesophageal reflux disease is associated with obesity and its prevalence is also growing worldwide. Numerous bariatric surgeries and endoscopic procedures have arisen to assist with weight loss and management of obesity-related conditions. However, the effect of these interventions on reflux is variable and the evidence is often conflicting. To date, Roux-en-Y gastric bypass remains the gold-standard for attaining both reflux and weight loss management, however novel endoscopic techniques are quickly becoming more prevalent as an alternative to surgery. This review aims to summarize currently available endoscopic and surgical weight loss procedures and their impact on reflux symptoms while emphasizing areas requiring additional investigation.
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