Related Experiment Video
Updated: Nov 23, 2025
08:20
Author Spotlight: Unveiling the Therapeutic Effects of FSN Treatment – Bridging Research and Clinical Applications in Neuropathic Pain
Published on: June 30, 2023
2.4K
Does subepineural injection damage the nerve integrity? A technical report from four amputated limbs
Sandeep Diwan1, Abhijit Nair2, Parag Sancheti3
1Department of Anesthesiology, Sancheti Hospital, Pune, India.
The Korean Journal of Pain
|December 31, 2020
Summary
Injecting local anesthetic (LA) inside the sciatic nerve sheath (subepineural) can cause neurological damage. For safe regional anesthesia, LA should be injected into the surrounding paraneural tissue, avoiding intraneural injection.
Area of Science:
- Anesthesiology
- Neurology
- Ultrasound Imaging
Background:
- Local anesthetic (LA) injection outside the nerve sheath is standard safe practice in regional anesthesia.
- Limited evidence exists regarding neurological complications from intraneural (subepineural) LA injection.
