Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Binkhorst iris clip lens.

Eye (London, England)·2024

Same author

Ophthalmological Examination and Imaging Features that Better Predict Risk of Angle Closure in Siblings.

Ophthalmology. Glaucoma·2024

Same author

Strabismus surgery educator - A novel eyeball model.

Indian journal of ophthalmology·2024

Same author

Effect of intravenous sedation on patients' visual experience and vital signs during cataract surgery under topical anesthesia: A randomized controlled trial.

Advances in ophthalmology practice and research·2023

Same author

Aqueous misdirection syndrome post silicone oil removal in a vitrectomized eye - a case report.

European journal of ophthalmology·2023

Same author

Evidence from the first Shared Medical Appointments (SMAs) randomised controlled trial in India: SMAs increase the satisfaction, knowledge, and medication compliance of patients with glaucoma.

PLOS global public health·2023

Search research articles

Related Experiment Video

Updated: Nov 23, 2025

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Radiation-induced neovascular glaucoma: A devastating disease.

Megha Gopalakrishna¹, Kavitha Srinivasan¹, Venkatesh Rengaraj¹

¹Department of Glaucoma, Aravind Eye Hospital, Puducherry, India.

Journal of Cancer Research and Therapeutics

|December 31, 2020

Summary

Radiotherapy can rarely cause neovascular glaucoma (NVG), a severe eye condition. Early diagnosis and multidisciplinary care are crucial for managing radiation-induced NVG and preserving vision.

Keywords:

Neovascular glaucoma ophthalmic complications of radiotherapy radiation

More Related Videos

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Published on: March 8, 2018

Related Experiment Videos

Last Updated: Nov 23, 2025

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Published on: March 8, 2018

Area of Science:

Ophthalmology
Oncology
Radiation Oncology

Background:

Neovascular glaucoma (NVG) is a severe secondary glaucoma.
Radiation therapy is a rare but recognized cause of NVG.
Nasal malignancies treated with radiotherapy pose a risk for ocular complications.

Observation:

A 50-year-old male developed NVG, enophthalmos, and dry eye three years post-radiotherapy for nasal chondrosarcoma.
The patient's ocular conditions were linked to radiation treatment fields involving the eye.

Findings:

The patient received a combination of topical antiglaucoma medications, retinal laser therapy, and intravitreal bevacizumab.
These interventions successfully managed the NVG, preventing a painful blind eye.

Implications:

Close collaboration between radiation oncologists, ENT specialists, and ophthalmologists is vital for patients receiving radiotherapy near the eyes.
Proactive monitoring and timely intervention can prevent severe visual impairment from radiation-induced NVG.
This case highlights the importance of a multidisciplinary approach in managing rare but devastating ocular side effects of cancer treatment.