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Updated: Nov 23, 2025

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
The contribution of multifocal visual evoked potentials in patients with optic neuritis and multiple sclerosis: a
Paraskevas Zafeiropoulos1, Andreas Katsanos2, George Kitsos2
1University Ophthalmology Clinic, Stavros Niarchos Avenue, 45500, Ioannina, Greece. pariszafeirop@gmail.com.
Purpose:
To review the evidence on the usefulness of the multifocal visual evoked potential (mfVEP) test in patients with optic neuritis (ON) and/or multiple sclerosis (MS).
Methods:
We critically review key published evidence on the use of mfVEP in ON/MS patients and its association with other functional and structural tests.
Results:
Multifocal VEP tests are useful in detecting abnormality in patients with ON/MS and monitor the progression of lesions (remyelination, atrophy). In addition, mfVEP has good correlation with conventional visual evoked potential (VEP), standard automated perimetry, optical coherence tomography and magnetic resonance imaging. In patients with ON, mfVEP might be useful in predicting the risk of conversion to MS.

