Amnion-Chorion Membrane in Open-Wound Approach for Localized Horizontal Ridge Augmentation: A Case Series Report.
Shan-Huey Yu1, Tae-Ju Oh1, Hom-Lay Wang1
1Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI.
Clinical Advances in Periodontics
|December 31, 2020
Summary
Amnion-chorion membranes facilitate open-wound healing for guided bone regeneration, reducing surgical trauma and preserving keratinized tissue. This approach offers a less invasive alternative for treating minor horizontal ridge defects.
Area of Science:
- Oral surgery
- Regenerative medicine
- Biomaterials
Background:
- Guided bone augmentation typically requires invasive mucoperiosteal flap release for primary closure, potentially reducing keratinized tissue and increasing morbidity.
- Amnion-chorion membranes (ACMs) are known to promote healing in chronic open wounds, suggesting potential application in oral surgery.
- Utilizing open-wound healing techniques could minimize surgical trauma and improve outcomes in guided bone regeneration.
Observation:
- ACMs were applied over bone graft material in localized horizontal ridge defects, with intentional gap healing and minor flap release.
- The surgical sites exhibited uneventful soft tissue healing and preserved keratinized tissue.
- Significant bone regeneration was observed in the augmented areas.
Findings:
- Controlled open-wound healing using ACMs is a viable approach for minor horizontal ridge defects.
- This method resulted in good bone regeneration and maintained keratinized tissue volume.
- The technique demonstrated successful soft tissue healing without major complications.
Implications:
- This less invasive approach reduces surgical trauma, chair time, and patient morbidity associated with traditional guided bone augmentation.
- ACMs show promise as a biomaterial for promoting healing in oral regenerative procedures.
- The findings suggest a paradigm shift towards less invasive techniques in treating localized bone defects.


