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Updated: Nov 23, 2025

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19
Published on: May 25, 2022
Monocular visual loss as the presenting symptom of COVID-19 infection
Ann P Murchison1, Ahmad Sweid2, Robin Dharia3
1Eye Emergency Room, Wills Eye Hospital & Associate Professor, Department of Emergency Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, United States; Oculoplastic and Orbital Surgery Service, Wills Eye Hospital, Philadelphia, PA, United States.
Background And Importance:
Additional time is needed to determine the exact impact of COVID-19 on acute cerebrovascular disease incidence, but recently published data has correlated COVID-19 to large vessel occlusion strokes.
Clinical Presentation:
We report the first case of central retinal artery occlusion (CRAO) as the initial manifestation of COVID-19 infection. Subsequent neuroimaging revealed a large thrombus extending into the internal carotid artery.
Conclusion:
This case illustrates the need to suspect COVID-19 infection in patients presenting with retinal arterial occlusion, including individuals who are asymptomatic or minimally symptomatic for COVID-19 infection.
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