Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ultrathin Dielectric Nanocoatings Enable Multifunctional High-Emissivity Silicon Surfaces.

ACS applied materials & interfaces·2026
Same author

A self-powered microsystem with efficient power management for continuous wireless sensing.

Microsystems & nanoengineering·2026
Same author

Wide field of view multifunctional solar sensor for photovoltaic power management via measurement of solar angle and intensity.

Microsystems & nanoengineering·2026
Same author

Correction: Adeel et al. Oxygen Consumption (VO<sub>2</sub>) and Surface Electromyography (sEMG) during Moderate-Strength Training Exercises. <i>Int. J. Environ. Res. Public Health</i> 2022, <i>19</i>, 2233.

International journal of environmental research and public health·2025
Same author

Power management technologies for triboelectric nanogenerators.

MRS bulletin·2025
Same author

Pilot study of using transcranial temporal interfering theta-burst stimulation for modulating motor excitability in rat.

Journal of neuroengineering and rehabilitation·2024

Related Experiment Video

Updated: Nov 23, 2025

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

21.5K

DNA Printing Integrated Multiplexer Driver Microelectronic Mechanical System Head (IDMH) and Microfluidic Flow

Jian-Chiun Liou1, Chih-Wei Peng1, Philippe Basset2

  • 1School of Biomedical Engineering, Taipei Medical University, Taipei 11031, Taiwan.

Micromachines
|January 1, 2021
PubMed
Summary

This study developed a DNA printing microelectronic mechanical system (MEMS) for precise liquid handling. The system enables rapid DNA deployment and accurate flow rate estimation, crucial for applications requiring small volumes of biological material.

Keywords:
DNA printingMEMSflow estimation

More Related Videos

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

15.2K
Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology
07:03

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

1.2K

Related Experiment Videos

Last Updated: Nov 23, 2025

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

21.5K
A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

15.2K
Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology
07:03

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

1.2K

Area of Science:

  • Biotechnology
  • Microfluidics
  • Materials Science

Background:

  • Accurate estimation of DNA liquid volume is critical for various biotechnological applications.
  • Existing methods for DNA deployment and flow rate measurement can be slow and imprecise.

Purpose of the Study:

  • To design and validate a three-dimensional (3D) microelectronic mechanical system (MEMS) chip for DNA printing.
  • To develop a method for rapid DNA deployment and precise microflow estimation.
  • To analyze the performance of the MEMS chip in terms of flow rate and power requirements.

Main Methods:

  • Fabrication of a 3D MEMS chip with varying heater dimensions and DNA bead placement.
  • Utilizing Flow-3D software for simulating internal flow fields and flow distribution.
  • Experimental measurement of chip generation processes, starting voltage curves, and flow rates.
  • Analysis of flow curves under different operating frequencies and pulse widths.

Main Results:

  • The MEMS chip demonstrated controlled ejection of DNA liquid with specific nozzle densities and heater sizes.
  • Flow rate simulations and experimental results correlated, providing insights into time and pressure requirements.
  • Optimized operating parameters (e.g., pulse width, power) achieved specific flow rates, such as 5.5 cc/min at 5 μs pulse width and 4.3-5.7 W power.

Conclusions:

  • The developed DNA printing MEMS system offers a viable solution for rapid and accurate DNA liquid handling.
  • The study provides a foundation for estimating flow rates and total ejected volumes in DNA-based applications.
  • This technology has potential applications in fields requiring precise manipulation of small liquid volumes.