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Updated: Nov 23, 2025
Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
Published on: November 17, 2014
Donor Choriocarcinoma Transmission From Solid Organ Transplantation: A Case Report
Daniela de Queiroz Moura1, Ramon Rawache2, Marília Ferreira Gomes Garcia3
1Kidney Transplantation Service at Walter Cantídio University Hospital, Fortaleza (CE), Brazil; Federal University of Ceará - Fortaleza (CE), Fortaleza (CE), Brazil.
Abstract:
Transplantation of any organ has some inherent risk of disease transmission, such as infection and malignancy. The present study aims to describe 2 cases of choriocarcinoma transmission after kidney and liver transplantation originating from the same patient. The donor was a 17-year-old woman who died of cerebral hemorrhage. Both organ recipients died of metastatic choriocarcinoma few months after the transplantation, within days after starting chemotherapy. Retrospective hCG (human chorionic gonadotropin hormone) analysis in donor's blood stored at the time of donation had a result of 9324 mIU/mL. Despite its rarity, clinicians should be aware of the risk of transplant-related choriocarcinoma from female donors in childbearing age. In some cases, hCG dosage should be performed before donation.
