Related Experiment Video
Updated: Jul 13, 2026
11:17
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Interpol review of controlled substances 2016-2019
Nicole S Jones1, Jeffrey H Comparin2
1RTI International, Applied Justice Research Division, Center for Forensic Sciences, 3040 E. Cornwallis Road, Research Triangle Park, NC, 22709-2194, USA.
Forensic Science International. Synergy
|January 1, 2021
Summary
This review summarizes forensic science literature on controlled substances from 2016-2019. It was presented at the 19th Interpol International Forensic Science Managers Symposium.
Area of Science:
- Forensic Chemistry
- Toxicology
- Drug Analysis
Background:
- The field of controlled substances is rapidly evolving, necessitating regular reviews of forensic literature.
- The Interpol International Forensic Science Managers Symposium serves as a key platform for disseminating such reviews.
Purpose of the Study:
- To provide a comprehensive overview of the forensic-relevant literature concerning controlled substances published between 2016 and 2019.
- To support forensic science managers and practitioners by highlighting key advancements and trends.
Main Methods:
- A systematic review of scientific literature published within the specified timeframe.
- Focus on publications relevant to the identification, analysis, and legal aspects of controlled substances.
Main Results:
- Key findings from the literature review on emerging trends in drug synthesis and detection.
- Identification of significant analytical methodologies and challenges in controlled substance analysis.
- Summary of legislative and forensic implications of new psychoactive substances.
Conclusions:
- The period 2016-2019 saw significant developments in controlled substance analysis and forensic science.
- Continuous literature review is crucial for maintaining expertise in forensic toxicology and drug analysis.
- The findings are intended to inform best practices in forensic laboratories worldwide.
Related Concept Videos
01:25Drug Regulation
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
01:25Drug Classes and Categories
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that possess the ability to eliminate pathogens or suppress their growth and reproduction can be grouped based on the organisms they target or their chemical structure. Furthermore, drugs can be divided into prescription, nonprescription, or controlled substances. Prescription medications, such as antibiotics, require oversight from a licensed healthcare...
01:19Pharmacovigilance
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
01:03Drug Control Governance: Regulatory Bodies and Their Impact
Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with a...
01:28Drug Products: Biologics, Biosimilars and Interchangeables
Biologics, derived from living sources such as humans, animals, or microorganisms, represent a significant category of pharmaceuticals. These complex molecules, developed through advanced biotechnological methods or purified from natural sources, include essential medical treatments like insulin and growth hormones. The complexity of biologics arises from their large molecular structures and the intricate processes required for their production, making them distinct from conventional...
01:22Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence
Generic intravenous (IV) drugs are considered bioequivalent to their branded counterparts due to their 100% bioavailability upon administration. However, variations in stability among different drug products can significantly influence their therapeutic performance, even if they are pharmaceutically equivalent.Cefuroxime, a prophylactic antimicrobial, is often used as a single-dose IV injection for patients undergoing coronary artery bypass grafting surgery. A 3 g dose typically provides...