Related Experiment Video
Updated: Nov 23, 2025

A Rabbit Aortic Valve Stenosis Model Induced by Direct Balloon Injury
Published on: March 31, 2023
A black heart: Aortic valve ochronosis secondary to alkaptonuria causing aortic stenosis
1Department of Cardiothoracic Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Abstract:
Alkaptonuria is a rare autosomal recessive genetic disorder where an accumulation of homogentisic acid in the tissues leads to ochronosis-a pathological dark pigmentation. It can affect various tissues and the weight bearing joints of the body, leading to degenerative arthropathy. On the rare occasion, it causes cardiac manifestations. We describe a case of aortic valve stenosis due to ochronosis secondary to alkaptonuria requiring aortic valve replacement.
More Related Videos
08:55Isolation and Characterization of Primary Rat Valve Interstitial Cells: A New Model to Study Aortic Valve Calcification
Published on: November 20, 2017
04:30Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat
Published on: February 4, 2021
Related Concept Videos
Mitral Stenosis I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation I: Introduction
Aneurysm I: Introduction
Aortic Regurgitation III: Medical Management
Mitral Stenosis II: Clinical features and Diagnostic Tests