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Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Design and synthesis of acrylate and acrylamide substituted pyrimidinediones as potential PPO herbicides
Won Hyung Lee1, Young Bin Kwon2, Jung Hee Kim2
1Central Research Institute, Kyung Nong Co. Ltd., 34-14 Summeori-gil, Gyeongju-si 38175, Gyeongsangbuk-do, Republic of Korea; School of Life Sciences and Biotechnology, Kyungpook National University, Daegu 41566, Republic of Korea.
Abstract:
PPO herbicides emerge to be widely use in the agricultural field and a focus of research to many scientists due to its environmentally-friendly properties. In lieu with this, this study presents acrylate and acrylamide substituted pyrimidinediones as PPO herbicide candidates. Most synthesized compounds exhibits herbicidal activities against both monocot and dicot weeds, especially, compound 5a which showed non-selective superior activity against the commercialized, Saflufenacil. Compound 5a was further tested for residual effect and showed promising results as shorter period is needed to cultivate the next crops. The synthesized acrylate and acrylamide substituted pyrimidinediones, especially, 5a could potentially be utilized in the development of commercial protoporphyrinogen oxidase inhibitors with further tests and studies.
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