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Murine Model of Controlled Cortical Impact for the Induction of Traumatic Brain Injury
Published on: August 16, 2019
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Traumatic maxillofacial and brain injuries: a systematic review.
E Z Goh1, N Beech2, N R Johnson3
1Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia.
International Journal of Oral and Maxillofacial Surgery
|January 3, 2021
Summary
Combined traumatic brain injury (TBI) and maxillofacial fractures often result from traffic accidents. Infection is a common complication, with delayed repair and low Glasgow Coma Score (GCS) increasing risk.
Area of Science:
- Trauma Surgery
- Neurosurgery
- Oral and Maxillofacial Surgery
Background:
- Concomitant traumatic brain injury (TBI) and maxillofacial fractures present significant clinical challenges.
- Understanding the epidemiology and outcomes of these combined injuries is crucial for developing effective management strategies.
Purpose of the Study:
- To systematically review the demographics, injury types, and complications associated with combined traumatic maxillofacial and brain injuries.
- To identify risk factors for complications and inform comprehensive health strategies for these patients.
Main Methods:
- Systematic literature search of PubMed and Scopus databases.
- Inclusion of clinical studies on combined maxillofacial and brain injuries published after 1990.
- Analysis of data from 15 eligible articles representing 1421 cases.
Main Results:
- The mean age of affected individuals was 38.3 years, with 79% being male.
- Traffic accidents were the most common cause (53.4%), and middle third facial fractures were most frequent (52.4%).
- Complications occurred in 24.5% of cases, with infection being the most common (36.7%).
Conclusions:
- Delayed surgical repair, low Glasgow Coma Score (GCS), and upper third facial fractures are significant risk factors for complications.
- Further research with robust longitudinal evaluations and clear TBI definitions is needed to understand risk factors and fracture pattern-GCS correlations.

