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An animal model for radiologic biliary interventional procedures.

C D Becker1, H J Burhenne

  • 1Department of Radiology, University of British Columbia, Vancouver, Canada.

Investigative Radiology
|January 1, 1988
PubMed
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A porcine model offers safe and easy access to the gallbladder and bile ducts for interventional radiology training and research. This animal model allows for repeated procedures, proving valuable for developing new techniques.

Area of Science:

  • Veterinary Radiology
  • Animal Models in Research
  • Interventional Radiology

Background:

  • Developing new interventional radiology techniques requires reliable animal models.
  • Existing models may lack easy and safe access to the gallbladder and bile ducts.
  • A need exists for a model suitable for procedural development and training.

Purpose of the Study:

  • To describe a porcine model for interventional biliary radiology.
  • To evaluate the feasibility of accessing the gallbladder and bile ducts in pigs.
  • To establish a model for training and research in biliary interventions.

Main Methods:

  • Utilized a porcine model for biliary system catheterization under fluoroscopic guidance.
  • Achieved permanent gallbladder access using a cholecystostomy catheter in ten pigs.

Related Experiment Videos

  • Performed common bile duct catheterization via the cystic duct in all animals.
  • Administered intramuscular sedation for repeated interventional procedures.

    • Main Results:

    • Successful catheterization of the porcine biliary system was demonstrated.
    • Permanent gallbladder access was established in the majority of pigs.
    • Common bile duct access through the cystic duct was consistently achieved.
    • The model supported repeated procedures under sedation over several weeks.

    Conclusions:

    • The porcine model provides a feasible and safe platform for interventional biliary radiology.
    • This model is suitable for procedural development, in vivo evaluation, and professional training.
    • Its capacity for serial procedures makes it valuable for long-term studies.