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Retrospective investigation of peripheric blood sampling in pediatric chalazion patients
1Department of Ophthalmology, Hatay State Hospital, Ekinci Mah. Cevreyolu Cad. Royals Park 13/1 No: 23, Antakya, Hatay, Turkey. cagriilhan@yahoo.com.
Insights
Pediatric chalazion patients exhibit lower serum ferritin levels compared to healthy children. This study investigated key nutrient levels in children with chalazion, finding a significant difference only in ferritin.
Area of Science:
- Ophthalmology
- Pediatrics
- Clinical Nutrition
Background:
- Chalazion is a common eyelid condition in children.
- Nutritional factors may influence the development or manifestation of chalazion.
- Understanding serum nutrient profiles can provide insights into pediatric health.
Purpose of the Study:
- To compare serum levels of thyroid hormones (FT3, FT4, TSH), vitamin B12, vitamin D3, folic acid, and ferritin.
- To investigate potential differences between children with chalazion and healthy controls.
Main Methods:
- Retrospective case-control study including pediatric chalazion patients and age/sex-matched healthy controls.
- Analysis of blood samples collected within six months of ophthalmological examination.
- Statistical comparison of serum levels for specified hormones and vitamins.
Main Results:
- Serum ferritin levels were significantly lower in the pediatric chalazion group (18.64 ± 8.97 μg/L) compared to the control group (35.46 ± 24.56 μg/L) (p=0.019).
- No significant differences were observed in serum levels of free triiodothyronine (FT3), free thyroxine (FT4), thyroid-stimulating hormone (TSH), vitamin B12, vitamin D3, or folic acid between the groups.
Conclusions:
- Pediatric chalazion patients demonstrate lower serum ferritin levels than their healthy counterparts.
- Ferritin deficiency may be associated with chalazion in children.
- Further research is warranted to explore the clinical implications of these findings.
Purpose:
To compare serum thyroid hormone, vitamin B12, vitamin D3, folic acid, and ferritin levels between pediatric chalazion patients and healthy children.
Methods:
Under 18-year-old chalazion patients and age- and sex-matched healthy controls were included into this retrospective case-control study. The peripheric blood sampling results obtained within six months from ophthalmological examination were investigated for statistical analysis. Free triiodothyronine (FT3), free thyroxine (FT4), thyroid-stimulating hormone (TSH), vitamin B12, vitamin D3, folic acid, and ferritin levels of the chalazion and control groups were compared.
Results:
The male-to-female ratio was 8/28 in the chalazion group and 22/48 in the control group (p > 0.05). The mean age was 13.891 ± 3.924 years (3-17) and 12.346 ± 3.963 years (4-17) in the groups, respectively (p > 0.05). The mean time between ophthalmological examination and peripheric blood sampling was 3.012 ± 2.201 months (0-6) and 2.092 ± 1.906 months (0-6) in the groups, respectively (p > 0.05). The mean value of ferritin was 18.641 ± 8.971 μg/L (5.900-38.600) in the chalazion group and 35.455 ± 24.561 μg/L (11.850-106.100) in the control group (p = 0.019). The mean values of FT3, FT4, TSH, vitamin B12, vitamin D3, and folic acid levels were similar between the groups (p > 0.05 for all).
Conclusion:
This study reports that pediatric chalazion patients have lower serum ferritin level than healthy children.
