Related Experiment Video
Updated: Nov 23, 2025

07:40
Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay
Published on: April 28, 2022
3.1K
Dermatologic Scar Assessment With Stereoscopic Imaging and Digital Three-Dimensional Models: A Validation Study.
Kristoffer Hendel1, Vinzent K Ortner1, Christine S K Fuchs1
1Department of Dermatology, Copenhagen University Hospital Bispebjerg and Frederiksberg, Nielsine Nielsens Vej 17, Copenhagen NV, 2400, Denmark.
Lasers in Surgery and Medicine
|January 3, 2021
Summary
A new handheld stereoscopic imaging system accurately measures scar dimensions. This technology offers repeatable results for both in-lab models and real-world scars, aiding in scar assessment.
Area of Science:
- Medical imaging
- Biomedical engineering
- Dermatology
Background:
- Scar assessment traditionally relies on subjective visual evaluation or manual measurements.
- Objective, quantitative scar assessment is crucial for treatment efficacy and research.
- Existing methods may lack precision, repeatability, or 3D visualization capabilities.
Purpose of the Study:
- To evaluate a novel handheld stereoscopic imaging system for scar visualization.
- To validate the accuracy and repeatability of morphometric scar measurements using this system.
- To assess both intra- and inter-investigator variability in scar assessment.
Main Methods:
- Utilized engineered metal plates with model scars (n=72) and in vivo scars (n=15).
- Scanned model scars six times by one investigator; in vivo scars once by three investigators.
- Assessed repeatability using coefficients of variation (CVs) and compared digital 3D estimates to known/measured dimensions.
Main Results:
- Intra-investigator scans of model scars showed high repeatability (CV: 1.8-3.1%) for volume, area, length, and depth.
- Inter-investigator scans of in vivo scars had slightly higher CVs (4.4-7.3%), with variations linked to respiratory movement.
- Digital 3D scar estimates strongly correlated with physical dimensions (P<0.001) and ruler measurements (P<0.001).
Conclusions:
- Handheld stereoscopic imaging provides accurate and repeatable scar morphometric estimates.
- Minimal intra- and inter-investigator variation was observed, enhancing objective scar assessment.
- Minimizing patient movement is key to optimizing measurement accuracy, especially for in vivo applications.

